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Is Type 2 Diabetes Genetic?

Type 2 diabetes is a chronic illness that affects more than 25 million Americans. Although it is not fully understood, it is thought to be caused by a combination of environmental and genetic factors.

Some people with type 2 diabetes have a family history of the disease, while others develop it without any known risk factors. Now You can Cure Diabetes Easily with Some Medications which you can buy from

As the understanding of type 2 diabetes continues to grow, researchers are increasingly asking if it is actually a genetic disorder.

The Role Of Genetics In Type 2 Diabetes

If you’ve been diagnosed with type 2 diabetes, there’s a good chance that you’re not the first person with diabetes in your family. You’re more likely to develop the condition if a parent or sibling has it.

Several gene mutations have been linked to the development of type 2 diabetes. These gene mutations can interact with the environment and each other to further increase your risk.

Type 2 diabetes is caused by both genetic and environmental factors.

Scientists have linked several gene mutations to a higher diabetes risk. Not everyone who carries a mutation will get diabetes. However, many people with diabetes do have one or more of these mutations.

It can be difficult to separate genetic risk from environmental risk. The latter is often influenced by your family members. For example, parents with nutrient-dense and balanced eating habits are likely to pass them on to the next generation.

On the other hand, genetics plays a big part in determining weight. Sometimes behaviours can’t take all the blame.

Which Genes Could Cause Type 2 Diabetes?

The following genes can lead to an increased likelihood that a person will develop type 2 diabetes:

CAPN10: This gene encodes enzymes that degrade proteins. It was the first gene that scientists confirmed had a definitive link with type 2 diabetes.

TCF7L2: This protein-coding gene has the strongest links to type 2 diabetes across all racial groups.

ABCC8: This gene may impair the release of insulin.

GCGR: This gene is a glucagon receptor.

GCK: This is a gene for the enzyme glucokinase, which speeds up glucose metabolism and acts as a glucose sensor.

GLUT2: This gene encodes for a glucose transporter, which regulates the entry of glucose into pancreatic beta cells.

SLC2A2: This gene regulates the entry of glucose in pancreatic beta cells and triggers insulin secretion.

HNF4A: This regulates genes in the liver and pancreas.

HNF4A: This is the insulin hormone gene.

KCNJ11: This is the gene for the potassium channels that trigger the release of insulin.

LPL: This is the enzyme lipoprotein lipase, which breaks down triglycerides (fats).

PPARG: This gene regulates fat cell differentiation.

PIK3R1: This gene has a role in insulin signalling.

Environmental factors can also influence if someone will develop type 2 diabetes, and we explain this next.

What Medicines Do I Need To Treat My Type 2 Diabetes?

Along with following your diabetes care plan, you may need diabetes medicines, which may include pills or medicines you inject under your skin, such as insulin. Over time, you may need more than one diabetes medicine to manage your blood glucose.

Even if you don’t take insulin, you may need it at special times, such as during pregnancy or if you are in the hospital. You also may need medicines for high blood pressure, high cholesterol, or other conditions.